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Purification and Characterization of a Novel and Robust L-Asparaginase Having Low-Glutaminase Activity from Bacillus licheniformis: In Vitro Evaluation of Anti-Cancerous Properties

L-asparaginase having low glutaminase has been a key therapeutic agent in the treatment of acute lymphpoblastic leukemia (A.L.L). In the present study, an extracellular L-asparaginase with low glutaminase activity, produced by Bacillus licheniformis was purified to homogeneity. Protein was found to...

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Detalles Bibliográficos
Autores principales: Mahajan, Richi V., Kumar, Vinod, Rajendran, Vinoth, Saran, Saurabh, Ghosh, Prahlad C., Saxena, Rajendra Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048267/
https://www.ncbi.nlm.nih.gov/pubmed/24905227
http://dx.doi.org/10.1371/journal.pone.0099037