Small Intestinal Intraepithelial TCRγδ(+) T Lymphocytes Are Present in the Premature Intestine but Selectively Reduced in Surgical Necrotizing Enterocolitis

BACKGROUND: Gastrointestinal barrier immaturity predisposes preterm infants to necrotizing enterocolitis (NEC). Intraepithelial lymphocytes (IEL) bearing the unconventional T cell receptor (TCR) γδ (γδ IEL) maintain intestinal integrity and prevent bacterial translocation in part through production...

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Detalles Bibliográficos
Autores principales: Weitkamp, Jörn-Hendrik, Rosen, Michael J., Zhao, Zhiguo, Koyama, Tatsuki, Geem, Duke, Denning, Timothy L., Rock, Michael T., Moore, Daniel J., Halpern, Melissa D., Matta, Pranathi, Denning, Patricia W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048281/
https://www.ncbi.nlm.nih.gov/pubmed/24905458
http://dx.doi.org/10.1371/journal.pone.0099042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048281/
https://www.ncbi.nlm.nih.gov/pubmed/24905458
http://dx.doi.org/10.1371/journal.pone.0099042

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