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Generation of a novel therapeutic peptide that depletes MDSC in tumor-bearing mice

Cancer immune evasion is an emerging hallmark of disease progression. Functional studies to understand the role of myeloid-derived suppressor cells (MDSC) in the tumor microenvironment however, are limited by the lack of available specific cell surface markers. We adapted a competitive peptide phage...

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Detalles Bibliográficos
Autores principales: Qin, Hong, Lerman, Beatrisa, Sakamaki, Ippei, Wei, Guowei, Cha, Soungchul, Rao, Sheetal S., Qian, Jianfei, Hailemichael, Yared, Nurieva, Roza, Dwyer, Karen C., Roth, Johannes, Yi, Qing, Overwijk, Willem W., Kwak, Larry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048321/
https://www.ncbi.nlm.nih.gov/pubmed/24859530
http://dx.doi.org/10.1038/nm.3560