The UPF1 RNA Surveillance Gene is Commonly Mutated in Pancreatic Adenosquamous Carcinoma

Pancreatic adenosquamous carcinoma (ASC) is an enigmatic and aggressive tumor that has a worse prognosis and higher metastatic potential than its adenocarcinoma counterpart. Here we report that ASC tumors frequently harbor somatically acquired mutations in the UPF1 gene, which encodes the core compo...

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Detalles Bibliográficos
Autores principales: Liu, Chen, Karam, Rachid, Zhou, YingQi, Su, Fang, Ji, Yuan, Li, Gang, Xu, GuoTong, Lu, LiXia, Wang, ChongRen, Song, MeiYi, Zhu, JingPing, Wang, YiRan, Zhao, YiFan, Foo, Wai Chin, Zuo, Mingxin, Valasek, Mark A, Javle, Milind, Wilkinson, Miles F, Lu, YanJun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048332/
https://www.ncbi.nlm.nih.gov/pubmed/24859531
http://dx.doi.org/10.1038/nm.3548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048332/
https://www.ncbi.nlm.nih.gov/pubmed/24859531
http://dx.doi.org/10.1038/nm.3548

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