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Continuous separation of protein loaded nanoparticles by simulated moving bed chromatography

For scale up and efficient production of protein loaded nanoparticles continuous separation by size exclusion chromatography in simulated moving bed (SMB) mode helps do reduce unbound protein concentration and increase yields for perfectly covered particles. Silica nanoparticles were loaded with an...

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Detalles Bibliográficos
Autores principales: Satzer, Peter, Wellhoefer, Martin, Jungbauer, Alois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048465/
https://www.ncbi.nlm.nih.gov/pubmed/24866563
http://dx.doi.org/10.1016/j.chroma.2014.04.093