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Continuous separation of protein loaded nanoparticles by simulated moving bed chromatography
For scale up and efficient production of protein loaded nanoparticles continuous separation by size exclusion chromatography in simulated moving bed (SMB) mode helps do reduce unbound protein concentration and increase yields for perfectly covered particles. Silica nanoparticles were loaded with an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048465/ https://www.ncbi.nlm.nih.gov/pubmed/24866563 http://dx.doi.org/10.1016/j.chroma.2014.04.093 |