Protein accumulation in the endoplasmic reticulum as a non-equilibrium phase transition

Several neurological disorders are associated with the aggregation of aberrant proteins, often localized in intracellular organelles such as the endoplasmic reticulum. Here we study protein aggregation kinetics by mean-field reactions and three dimensional Monte carlo simulations of diffusion-limite...

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Detalles Bibliográficos
Autores principales: Budrikis, Zoe, Costantini, Giulio, La Porta, Caterina A. M., Zapperi, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048836/
https://www.ncbi.nlm.nih.gov/pubmed/24722051
http://dx.doi.org/10.1038/ncomms4620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048836/
https://www.ncbi.nlm.nih.gov/pubmed/24722051
http://dx.doi.org/10.1038/ncomms4620

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