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Lentiviral vector transduction of spermatozoa as a tool for the study of early development

Spermatozoa and lentiviruses are two of nature’s most efficient gene delivery vehicles. Both can be genetically modified and used independently for the generation of transgenic animals or gene transfer/therapy of inherited disorders. Here we show that mature spermatozoa can be directly transduced wi...

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Detalles Bibliográficos
Autores principales: Chandrashekran, Anil, Isa, Ihsan, Dudhia, Jayesh, Thrasher, Adrian J., Dibb, Nicholas, Casimir, Colin, Readhead, Carol, Winston, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048842/
https://www.ncbi.nlm.nih.gov/pubmed/24918038
http://dx.doi.org/10.1016/j.fob.2014.02.008