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The role of Cysteine 227 in subcellular localization, water permeability, and multimerization of aquaporin-11

Aquaporin-11 (AQP11) is the latest member of the mammalian water channel protein family to be described. Recent in vivo studies have shown that mutation at Cys(227) causes renal failure. However the importance of Cys(227) for the molecular function of AQP11 is largely unknown. In this study, we exam...

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Detalles Bibliográficos
Autores principales: Takahashi, Saki, Muta, Kanako, Sonoda, Hiroko, Kato, Ayaka, Abdeen, Ahmed, Ikeda, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048847/
https://www.ncbi.nlm.nih.gov/pubmed/24918044
http://dx.doi.org/10.1016/j.fob.2014.03.005