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RNAi-Mediated Gene silencing in Zebrafish Triggered by Convergent Transcription

RNAi based strategies to induce gene silencing are commonly employed in numerous model organisms but have not been extensively used in zebrafish. We found that introduction of transgenes containing convergent transcription units in zebrafish embryos induced stable transcriptional gene silencing (TGS...

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Detalles Bibliográficos
Autores principales: Andrews, Omozusi E., Cha, Diana J., Wei, Chunyao, Patton, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048883/
https://www.ncbi.nlm.nih.gov/pubmed/24909225
http://dx.doi.org/10.1038/srep05222