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Invasion of the Central Nervous System by Cryptococcus neoformans Requires a Secreted Fungal Metalloprotease

Cryptococcus spp. cause life-threatening fungal infection of the central nervous system (CNS), predominantly in patients with a compromised immune system. Why Cryptococcus neoformans has this remarkable tropism for the CNS is not clear. Recent research on cerebral pathogenesis of C. neoformans revea...

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Detalles Bibliográficos
Autores principales: Vu, Kiem, Tham, Rick, Uhrig, John P., Thompson, George R., Na Pombejra, Sarisa, Jamklang, Mantana, Bautos, Jennifer M., Gelli, Angie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049100/
https://www.ncbi.nlm.nih.gov/pubmed/24895304
http://dx.doi.org/10.1128/mBio.01101-14