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Invasion of the Central Nervous System by Cryptococcus neoformans Requires a Secreted Fungal Metalloprotease
Cryptococcus spp. cause life-threatening fungal infection of the central nervous system (CNS), predominantly in patients with a compromised immune system. Why Cryptococcus neoformans has this remarkable tropism for the CNS is not clear. Recent research on cerebral pathogenesis of C. neoformans revea...
Autores principales: | Vu, Kiem, Tham, Rick, Uhrig, John P., Thompson, George R., Na Pombejra, Sarisa, Jamklang, Mantana, Bautos, Jennifer M., Gelli, Angie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049100/ https://www.ncbi.nlm.nih.gov/pubmed/24895304 http://dx.doi.org/10.1128/mBio.01101-14 |
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