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Mycobacterium tuberculosis Lsr2 Is a Global Transcriptional Regulator Required for Adaptation to Changing Oxygen Levels and Virulence

To survive a dynamic host environment, Mycobacterium tuberculosis must endure a series of challenges, from reactive oxygen and nitrogen stress to drastic shifts in oxygen availability. The mycobacterial Lsr2 protein has been implicated in reactive oxygen defense via direct protection of DNA. To exam...

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Detalles Bibliográficos
Autores principales: Bartek, I. L., Woolhiser, L. K., Baughn, A. D., Basaraba, R. J., Jacobs, W. R., Lenaerts, A. J., Voskuil, M. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049101/
https://www.ncbi.nlm.nih.gov/pubmed/24895305
http://dx.doi.org/10.1128/mBio.01106-14