Synthesis and Biophysical Properties of C5-Functionalized LNA (Locked Nucleic Acid)

[Image: see text] Oligonucleotides modified with conformationally restricted nucleotides such as locked nucleic acid (LNA) monomers are used extensively in molecular biology and medicinal chemistry to modulate gene expression at the RNA level. Major efforts have been devoted to the design of LNA der...

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Detalles Bibliográficos
Autores principales: Kumar, Pawan, Østergaard, Michael E., Baral, Bharat, Anderson, Brooke A., Guenther, Dale C., Kaura, Mamta, Raible, Daniel J., Sharma, Pawan K., Hrdlicka, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049237/
https://www.ncbi.nlm.nih.gov/pubmed/24825249
http://dx.doi.org/10.1021/jo500614a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049237/
https://www.ncbi.nlm.nih.gov/pubmed/24825249
http://dx.doi.org/10.1021/jo500614a

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