Mutations of NOTCH3 in childhood pulmonary arterial hypertension

Mutations of BMPR2 and other TGF-β superfamily genes have been reported in pulmonary arterial hypertension (PAH). However, 60–90% of idiopathic PAH cases have no mutations in these genes. Recently, the expression of NOTCH3 was shown to be increased in the pulmonary artery smooth muscle cells of PAH...

Descripción completa

Detalles Bibliográficos
Autores principales: Chida, Ayako, Shintani, Masaki, Matsushita, Yoshihisa, Sato, Hiroki, Eitoku, Takahiro, Nakayama, Tomotaka, Furutani, Yoshiyuki, Hayama, Emiko, Kawamura, Yoichi, Inai, Kei, Ohtsuki, Shinichi, Saji, Tsutomu, Nonoyama, Shigeaki, Nakanishi, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049363/
https://www.ncbi.nlm.nih.gov/pubmed/24936512
http://dx.doi.org/10.1002/mgg3.58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049363/
https://www.ncbi.nlm.nih.gov/pubmed/24936512
http://dx.doi.org/10.1002/mgg3.58

Ejemplares similares