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Induction of proline-rich tyrosine kinase 2 activation-mediated C6 glioma cell invasion after anti-vascular endothelial growth factor therapy

BACKGROUND: Anti-angiogenic therapy inhibits tumor growth and is considered as a potential clinical therapy for malignant glioma. However, inevitable recurrences and unexpected tumor resistance, particularly increased invasion ability of glioma cell, were observed after anti-angiogenic treatment. Th...

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Detalles Bibliográficos
Autores principales: Xu, Cheng-Shi, Wang, Ze-Fen, Dai, Li-Ming, Chu, Sheng-Hua, Gong, Ling-Ling, Yang, Ming-Huan, Li, Zhi-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049398/
https://www.ncbi.nlm.nih.gov/pubmed/24884636
http://dx.doi.org/10.1186/1479-5876-12-148