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Mitochondrial haplogroups modify the effect of black carbon on age-related cognitive impairment

BACKGROUND: Traffic-related air pollution has been linked with impaired cognition in older adults, possibly due to effects of oxidative stress on the brain. Mitochondria are the main source of cellular oxidation. Haplogroups in mitochondrial DNA (mtDNA) mark individual differences in oxidative poten...

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Detalles Bibliográficos
Autores principales: Colicino, Elena, Power, Melinda C, Cox, David G, Weisskopf, Marc G, Hou, Lifang, Alexeeff, Stacy E, Sanchez-Guerra, Marco, Vokonas, Pantel, Spiro III, Avron, Schwartz, Joel, Baccarelli, Andrea A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049407/
https://www.ncbi.nlm.nih.gov/pubmed/24884505
http://dx.doi.org/10.1186/1476-069X-13-42