Omega-3 Free Fatty Acids Suppress Macrophage Inflammasome Activation by Inhibiting NF-κB Activation and Enhancing Autophagy

The omega-3 (ω3) fatty acid docosahexaenoic acid (DHA) can suppress inflammation, specifically IL-1β production through poorly understood molecular mechanisms. Here, we show that DHA reduces macrophage IL-1β production by limiting inflammasome activation. Exposure to DHA reduced IL-1β production by...

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Detalles Bibliográficos
Autores principales: Williams-Bey, Yolanda, Boularan, Cedric, Vural, Ali, Huang, Ning-Na, Hwang, Il-Young, Shan-Shi, Chong, Kehrl, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049592/
https://www.ncbi.nlm.nih.gov/pubmed/24911523
http://dx.doi.org/10.1371/journal.pone.0097957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049592/
https://www.ncbi.nlm.nih.gov/pubmed/24911523
http://dx.doi.org/10.1371/journal.pone.0097957

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