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Omega-3 Free Fatty Acids Suppress Macrophage Inflammasome Activation by Inhibiting NF-κB Activation and Enhancing Autophagy

The omega-3 (ω3) fatty acid docosahexaenoic acid (DHA) can suppress inflammation, specifically IL-1β production through poorly understood molecular mechanisms. Here, we show that DHA reduces macrophage IL-1β production by limiting inflammasome activation. Exposure to DHA reduced IL-1β production by...

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Detalles Bibliográficos
Autores principales:	Williams-Bey, Yolanda, Boularan, Cedric, Vural, Ali, Huang, Ning-Na, Hwang, Il-Young, Shan-Shi, Chong, Kehrl, John H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049592/ https://www.ncbi.nlm.nih.gov/pubmed/24911523 http://dx.doi.org/10.1371/journal.pone.0097957

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