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A Defective TLR4 Signaling for IFN-β Expression Is Responsible for the Innately Lower Ability of BALB/c Macrophages to Produce NO in Response to LPS as Compared to C57BL/6
C57BL/6 mice macrophages innately produce higher levels of NO than BALB/c cells when stimulated with LPS. Here, we investigated the molecular events that account for this intrinsic differential production of NO. We found that the lower production of NO in BALB/c is not due to a subtraction of L-argi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049611/ https://www.ncbi.nlm.nih.gov/pubmed/24911280 http://dx.doi.org/10.1371/journal.pone.0098913 |