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Structure and Activity of Streptococcus pyogenes SipA: A Signal Peptidase-Like Protein Essential for Pilus Polymerisation

The pili expressed on the surface of the human pathogen Streptococcus pyogenes play an important role in host cell attachment, colonisation and pathogenesis. These pili are built from two or three components, an adhesin subunit at the tip, a major pilin that forms a polymeric shaft, and a basal pili...

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Detalles Bibliográficos
Autores principales: Young, Paul G., Proft, Thomas, Harris, Paul W. R., Brimble, Margaret A., Baker, Edward N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049620/
https://www.ncbi.nlm.nih.gov/pubmed/24911348
http://dx.doi.org/10.1371/journal.pone.0099135