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Structure and Activity of Streptococcus pyogenes SipA: A Signal Peptidase-Like Protein Essential for Pilus Polymerisation
The pili expressed on the surface of the human pathogen Streptococcus pyogenes play an important role in host cell attachment, colonisation and pathogenesis. These pili are built from two or three components, an adhesin subunit at the tip, a major pilin that forms a polymeric shaft, and a basal pili...
Autores principales: | Young, Paul G., Proft, Thomas, Harris, Paul W. R., Brimble, Margaret A., Baker, Edward N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049620/ https://www.ncbi.nlm.nih.gov/pubmed/24911348 http://dx.doi.org/10.1371/journal.pone.0099135 |
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