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Non-invasive imaging of Toll-like receptor 5 expression using (131)I-labeled mAb in the mice bearing H22 tumors

Toll-like receptor 5 (TLR5) is overexpressed in several cancers and metastases, and presents an enticing target for molecular imaging of primary tumors. In the present study, (131)I-anti-TLR5 monoclonal antibody (mAb) was evaluated for its use as a novel radiotracer for imaging hepatocarcinoma in mi...

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Detalles Bibliográficos
Autores principales: YANG, CHANGYA, YUN, QINGYING, SUN, HUKUI, YANG, GUANGJIE, LIANG, TING, ZHANG, CHAO, SONG, JING, HAN, JIANKUI, HOU, GUIHUA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049746/
https://www.ncbi.nlm.nih.gov/pubmed/24932259
http://dx.doi.org/10.3892/ol.2014.2025