O(6)-methylguanine-DNA methyltransferase as a prognostic and predictive marker for basal-like breast cancer treated with cyclophosphamide-based chemotherapy

The O(6)-methylguanine-DNA methyltransferase (MGMT) protein protects cells from alkylating agents by removing alkyl groups from the O(6)-position of guanine. However, its effect on DNA damage induced by cyclophosphamide (CPM) is unclear. The present study investigated whether MGMT expression was cor...

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Detalles Bibliográficos
Autores principales: ISONO, SAYURI, FUJISHIMA, MAKOTO, AZUMI, TATSUYA, HASHIMOTO, YUKIHIKO, KOMOIKE, YOSHIFUMI, YUKAWA, MASAO, WATATANI, MASAHIRO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049755/
https://www.ncbi.nlm.nih.gov/pubmed/24932232
http://dx.doi.org/10.3892/ol.2014.1985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049755/
https://www.ncbi.nlm.nih.gov/pubmed/24932232
http://dx.doi.org/10.3892/ol.2014.1985

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