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Pannexin-1 Is Blocked by Its C-Terminus through a Delocalized Non-Specific Interaction Surface
The Pannexin-1 (Panx1) channel is known to become activated under a variety of physiological conditions resulting in the release of medium-sized molecules such as ATP and amino acids from the cell. The detailed molecular mechanism of activation of the channel resulting in the opening of the Pannexin...
Autores principales: | Dourado, Michelle, Wong, Evera, Hackos, David H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049774/ https://www.ncbi.nlm.nih.gov/pubmed/24911976 http://dx.doi.org/10.1371/journal.pone.0099596 |
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