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Rap1 signaling in endothelial barrier control

The small G-protein Rap1 plays an important role in the regulation of endothelial barrier function, a process controlled largely by cell–cell adhesions and their connection to the actin cytoskeleton. During the various stages of barrier dynamics, different guanine nucleotide exchange factors (GEFs)...

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Detalles Bibliográficos
Autores principales: Pannekoek, Willem-Jan, Post, Anneke, Bos, Johannes L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049856/
https://www.ncbi.nlm.nih.gov/pubmed/24714377
http://dx.doi.org/10.4161/cam.27352