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Clostridium difficile binary toxin CDT: Mechanism, epidemiology, and potential clinical importance

Binary toxin (CDT) is frequently observed in Clostridium difficile strains associated with increased severity of C. difficile infection (CDI). CDT belongs to the family of binary ADP-ribosylating toxins consisting of two separate toxin components: CDTa, the enzymatic ADP-ribosyltransferase which mod...

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Detalles Bibliográficos
Autores principales: Gerding, Dale N, Johnson, Stuart, Rupnik, Maja, Aktories, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049931/
https://www.ncbi.nlm.nih.gov/pubmed/24253566
http://dx.doi.org/10.4161/gmic.26854