Most Human Proteins Made in Both Nucleus and Cytoplasm Turn Over within Minutes

In bacteria, protein synthesis can be coupled to transcription, but in eukaryotes it is believed to occur solely in the cytoplasm. Using pulses as short as 5 s, we find that three analogues – L-azidohomoalanine, puromycin (detected after attaching fluors using ‘click’ chemistry or immuno-labeling),...

Descripción completa

Detalles Bibliográficos
Autores principales: Baboo, Sabyasachi, Bhushan, Bhaskar, Jiang, Haibo, Grovenor, Chris R. M., Pierre, Philippe, Davis, Benjamin G., Cook, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050049/
https://www.ncbi.nlm.nih.gov/pubmed/24911415
http://dx.doi.org/10.1371/journal.pone.0099346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050049/
https://www.ncbi.nlm.nih.gov/pubmed/24911415
http://dx.doi.org/10.1371/journal.pone.0099346

Ejemplares similares