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Establishment of a replication fork barrier following induction of DNA binding in mammalian cells

Understanding the mechanisms that lead to replication fork blocks (RFB) and the means to bypass them is important given the threat that they represent for genome stability if inappropriately handled. Here, to study this issue in mammals, we use integrated arrays of the LacO and/or TetO as a tractabl...

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Detalles Bibliográficos
Autores principales: Beuzer, Paolo, Quivy, Jean-Pierre, Almouzni, Geneviève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050166/
https://www.ncbi.nlm.nih.gov/pubmed/24675882
http://dx.doi.org/10.4161/cc.28627