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Establishment of a mast cell line, NCL-2, without Kit mutation, derived from NC mouse bone marrow

Immortal mast cell lines, such as RBL-2H3 and HMC-1 cells, are commonly utilized to investigate the function of mast cells. However, they are tumor cells carrying a gain-of-function mutation of Kit. We established an immortal mast cell line without Kit mutation, NCL-2, derived from NC mouse bone mar...

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Detalles Bibliográficos
Autores principales: Hiragun, Takaaki, Yanase, Yuhki, Okabe, Tsutomu, Hiragun, Makiko, Kawai, Mikio, Hide, Michihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050185/
https://www.ncbi.nlm.nih.gov/pubmed/24918047
http://dx.doi.org/10.1016/j.fob.2014.03.011