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Molecular dynamics modeling the synthetic and biological polymers interactions pre-studied via docking: Anchors modified polyanions interference with the HIV-1 fusion mediator

In previous works we reported the design, synthesis and in vitro evaluations of synthetic anionic polymers modified by alicyclic pendant groups (hydrophobic anchors), as a novel class of inhibitors of the human immunodeficiency virus type 1 (HIV-1) entry into human cells. Recently, these synthetic p...

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Detalles Bibliográficos
Autores principales: Tsvetkov, Vladimir B., Serbin, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050303/
https://www.ncbi.nlm.nih.gov/pubmed/24862639
http://dx.doi.org/10.1007/s10822-014-9749-8