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Evaluation of Various Factors Affecting Bioconversion of l-Tyrosine to l-DOPA by Yeast Yarrowia lipolytica-NCIM 3450 Using Response Surface Methodology

ABSTRACT: 3,4-Dihydroxy l-phenylalanine (l-DOPA) is considered a potent drug for the treatment of Parkinson disease. Physical and nutritional parameters where optimized by using Yarrowia lipolytica-NCIM 3450 to accomplished the highest production of l-DOPA. Screenings of critical components were com...

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Detalles Bibliográficos
Autores principales: Gurme, Swati T., Surwase, Shripad N., Patil, Sushama A., Jadhav, Jyoti P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050310/
https://www.ncbi.nlm.nih.gov/pubmed/24955295
http://dx.doi.org/10.1007/s13659-014-0017-3