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Bone Marrow Endosteal Mesenchymal Progenitors Depend on HIF Factors for Maintenance and Regulation of Hematopoiesis
Maintenance and differentiation of hematopoietic stem cells (HSCs) is regulated through cell-autonomous and non-cell-autonomous mechanisms within specialized bone marrow microenvironments. Recent evidence demonstrates that signaling by HIF-1α contributes to cell-autonomous regulation of HSC maintena...
Autores principales: | Guarnerio, Jlenia, Coltella, Nadia, Ala, Ugo, Tonon, Giovanni, Pandolfi, Pier Paolo, Bernardi, Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050345/ https://www.ncbi.nlm.nih.gov/pubmed/24936467 http://dx.doi.org/10.1016/j.stemcr.2014.04.002 |
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