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X Chromosome of Female Cells Shows Dynamic Changes in Status during Human Somatic Cell Reprogramming
Induced pluripotent stem cells (iPSCs) acquire embryonic stem cell (ESC)-like epigenetic states, including the X chromosome. Previous studies reported that human iPSCs retain the inactive X chromosome of parental cells, or acquire two active X chromosomes through reprogramming. Most studies investig...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050354/ https://www.ncbi.nlm.nih.gov/pubmed/24936474 http://dx.doi.org/10.1016/j.stemcr.2014.04.003 |