Conformational dynamics of ligand-dependent alternating access in LeuT

The leucine transporter (LeuT) from Aquifex aeolicus is a bacterial homolog of neurotransmitter:sodium symporters (NSS) that catalyze reuptake of neurotransmitters at the synapse. Crystal structures of wild type (WT) and mutants of LeuT have been interpreted as conformational states in the coupled t...

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Detalles Bibliográficos
Autores principales: Kazmier, Kelli, Sharma, Shruti, Quick, Matthias, Islam, Shahidul M., Roux, Benoit, Weinstein, Harel, Javitch, Jonathan A., Mchaourab, Hassane S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050370/
https://www.ncbi.nlm.nih.gov/pubmed/24747939
http://dx.doi.org/10.1038/nsmb.2816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050370/
https://www.ncbi.nlm.nih.gov/pubmed/24747939
http://dx.doi.org/10.1038/nsmb.2816

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