Cell-State Transitions Regulated by SLUG Are Critical for Tissue Regeneration and Tumor Initiation

Perturbations in stem cell activity and differentiation can lead to developmental defects and cancer. We use an approach involving a quantitative model of cell-state transitions in vitro to gain insights into how SLUG/SNAI2, a key developmental transcription factor, modulates mammary epithelial stem...

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Detalles Bibliográficos
Autores principales: Phillips, Sarah, Prat, Aleix, Sedic, Maja, Proia, Theresa, Wronski, Ania, Mazumdar, Sohini, Skibinski, Adam, Shirley, Stephanie H., Perou, Charles M., Gill, Grace, Gupta, Piyush B., Kuperwasser, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050485/
https://www.ncbi.nlm.nih.gov/pubmed/24936451
http://dx.doi.org/10.1016/j.stemcr.2014.03.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050485/
https://www.ncbi.nlm.nih.gov/pubmed/24936451
http://dx.doi.org/10.1016/j.stemcr.2014.03.008

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