Talin regulates moesin–NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis

Invadopodia are actin-rich protrusions that degrade the extracellular matrix and are required for stromal invasion, intravasation, and metastasis. The role of the focal adhesion protein talin in regulating these structures is not known. Here, we demonstrate that talin is required for invadopodial ma...

Descripción completa

Detalles Bibliográficos
Autores principales: Beaty, Brian T., Wang, Yarong, Bravo-Cordero, Jose Javier, Sharma, Ved P., Miskolci, Veronika, Hodgson, Louis, Condeelis, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050723/
https://www.ncbi.nlm.nih.gov/pubmed/24891603
http://dx.doi.org/10.1083/jcb.201312046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050723/
https://www.ncbi.nlm.nih.gov/pubmed/24891603
http://dx.doi.org/10.1083/jcb.201312046

Ejemplares similares