BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis

During meiosis, DNA damage response (DDR) proteins induce transcriptional silencing of unsynapsed chromatin, including the constitutively unsynapsed XY chromosomes in males. DDR proteins are also implicated in double strand break repair during meiotic recombination. Here, we address the function of...

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Detalles Bibliográficos
Autores principales: Broering, Tyler J., Alavattam, Kris G., Sadreyev, Ruslan I., Ichijima, Yosuke, Kato, Yasuko, Hasegawa, Kazuteru, Camerini-Otero, R. Daniel, Lee, Jeannie T., Andreassen, Paul R., Namekawa, Satoshi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050732/
https://www.ncbi.nlm.nih.gov/pubmed/24914237
http://dx.doi.org/10.1083/jcb.201311050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050732/
https://www.ncbi.nlm.nih.gov/pubmed/24914237
http://dx.doi.org/10.1083/jcb.201311050

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