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Lipoic acid, but not tempol, preserves vascular compliance and decreases medial calcification in a model of elastocalcinosis

Vascular calcification decreases compliance and increases morbidity. Mechanisms of this process are unclear. The role of oxidative stress and effects of antioxidants have been poorly explored. We investigated effects of the antioxidants lipoic acid (LA) and tempol in a model of atherosclerosis assoc...

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Detalles Bibliográficos
Autores principales: Bassi, E., Liberman, M., Martinatti, M.K., Bortolotto, L.A., Laurindo, F.R.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051185/
https://www.ncbi.nlm.nih.gov/pubmed/24519127
http://dx.doi.org/10.1590/1414-431X20133193