The Challenge of Targeting Notch in Hematologic Malignancies

Notch signaling can play oncogenic and tumor suppressor roles depending on cell type. Hematologic malignancies encompass a wide range of transformed cells, and consequently the roles of Notch are diverse in these diseases. For example Notch is a potent T-cell oncogene, with >50% of T-cell acute l...

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Detalles Bibliográficos
Autores principales: Hernandez Tejada, Fiorela N., Galvez Silva, Jorge R., Zweidler-McKay, Patrick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051192/
https://www.ncbi.nlm.nih.gov/pubmed/24959528
http://dx.doi.org/10.3389/fped.2014.00054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051192/
https://www.ncbi.nlm.nih.gov/pubmed/24959528
http://dx.doi.org/10.3389/fped.2014.00054

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