Enhancing the Quality of H/D Exchange Measurements with Mass Spectrometry Detection in Disulfide-Rich Proteins Using Electron Capture Dissociation

[Image: see text] Hydrogen/deuterium exchange (HDX) mass spectrometry (MS) has become a potent technique to probe higher-order structures, dynamics, and interactions of proteins. While the range of proteins amenable to interrogation by HDX MS continues to expand at an accelerating pace, there are st...

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Detalles Bibliográficos
Autores principales: Bobst, Cedric E., Kaltashov, Igor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051250/
https://www.ncbi.nlm.nih.gov/pubmed/24820935
http://dx.doi.org/10.1021/ac500904p

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051250/
https://www.ncbi.nlm.nih.gov/pubmed/24820935
http://dx.doi.org/10.1021/ac500904p

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