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Tissue Kallikrein-Modified Human Endothelial Progenitor Cell Implantation Improves Cardiac Function via Enhanced Activation of Akt and Increased Angiogenesis

Endothelial progenitor cells (EPCs) have been shown to enhance angiogenesis not only by incorporating into the vasculature but also by secreting cytokines, thereby serving as an ideal vehicle for gene transfer. As tissue kallikrein (TK) has pleiotropic effects in inhibiting apoptosis and oxidative s...

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Detalles Bibliográficos
Autores principales: Yao, Yuyu, Sheng, Zulong, Li, Yefei, Fu, Cong, Ma, Genshan, Liu, Naifeng, Chao, Julie, Chao, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051305/
https://www.ncbi.nlm.nih.gov/pubmed/23508045
http://dx.doi.org/10.1038/labinvest.2013.48