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A combination of p300 and Braf expression in the diagnosis and prognosis of melanoma

BACKGROUND: To date only a handful of drugs are available for the treatment of melanoma. Among them vemurafenib, a Braf(V600E) specific inhibitor, showed promising results in terms of response rate and increase in median survival time. However, its effectiveness is limited by development of resistan...

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Detalles Bibliográficos
Autores principales: Bhandaru, Madhuri, Ardekani, Gholamreza Safaee, Zhang, Guohong, Martinka, Magdalena, McElwee, Kevin J, Li, Gang, Rotte, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051389/
https://www.ncbi.nlm.nih.gov/pubmed/24893747
http://dx.doi.org/10.1186/1471-2407-14-398