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A combination of p300 and Braf expression in the diagnosis and prognosis of melanoma
BACKGROUND: To date only a handful of drugs are available for the treatment of melanoma. Among them vemurafenib, a Braf(V600E) specific inhibitor, showed promising results in terms of response rate and increase in median survival time. However, its effectiveness is limited by development of resistan...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051389/ https://www.ncbi.nlm.nih.gov/pubmed/24893747 http://dx.doi.org/10.1186/1471-2407-14-398 |