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Improved Model to Predict the Free Energy Contribution of Trinucleotide Bulges to RNA Duplex Stability
[Image: see text] Trinucleotide bulges in RNA commonly occur in nature. Yet, little data exists concerning the thermodynamic parameters of this motif. Algorithms that predict RNA secondary structure from sequence currently attribute a constant free energy value of 3.2 kcal/mol to all trinucleotide b...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051427/ https://www.ncbi.nlm.nih.gov/pubmed/24853497 http://dx.doi.org/10.1021/bi500204e |