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Improved Model to Predict the Free Energy Contribution of Trinucleotide Bulges to RNA Duplex Stability

[Image: see text] Trinucleotide bulges in RNA commonly occur in nature. Yet, little data exists concerning the thermodynamic parameters of this motif. Algorithms that predict RNA secondary structure from sequence currently attribute a constant free energy value of 3.2 kcal/mol to all trinucleotide b...

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Detalles Bibliográficos
Autores principales:	Murray, Meghan H., Hard, Jessicah A., Znosko, Brent M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051427/ https://www.ncbi.nlm.nih.gov/pubmed/24853497 http://dx.doi.org/10.1021/bi500204e

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