Cycloheximide and Actiphenol Production in Streptomyces sp. YIM56141 Governed by Single Biosynthetic Machinery Featuring an Acyltransferase-less Type I Polyketide Synthase

[Image: see text] Cycloheximide (1) and actiphenol (2) have been isolated from numerous Streptomyces species. Cloning, sequencing, and characterization of a gene cluster from Streptomyces sp. YIM65141 now establish that 1 and 2 production is governed by single biosynthetic machinery. Biosynthesis of...

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Detalles Bibliográficos
Autores principales: Yin, Min, Yan, Yijun, Lohman, Jeremy R., Huang, Sheng-Xiong, Ma, Ming, Zhao, Guang-Rong, Xu, Li-Hua, Xiang, Wensheng, Shen, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051428/
https://www.ncbi.nlm.nih.gov/pubmed/24815182
http://dx.doi.org/10.1021/ol501179w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051428/
https://www.ncbi.nlm.nih.gov/pubmed/24815182
http://dx.doi.org/10.1021/ol501179w

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