In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27

The DNA of several pathogens is very rich in AT base pairs. Typical examples include the malaria parasite Plasmodium falciparum and the causative agents of trichomoniasis and trypanosomiases. This fact has prompted studies of drugs which interact with the minor groove of DNA, some of which are used...

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Detalles Bibliográficos
Autores principales: Acosta-Reyes, Francisco J., Dardonville, Christophe, de Koning, Harry P., Natto, Manal, Subirana, Juan A., Campos, J. Lourdes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051503/
https://www.ncbi.nlm.nih.gov/pubmed/24914972
http://dx.doi.org/10.1107/S139900471400697X

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051503/
https://www.ncbi.nlm.nih.gov/pubmed/24914972
http://dx.doi.org/10.1107/S139900471400697X

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