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Identification of Continuous Human B-Cell Epitopes in the VP35, VP40, Nucleoprotein and Glycoprotein of Ebola Virus

Ebola virus (EBOV) is a highly virulent human pathogen. Recovery of infected patients is associated with efficient EBOV-specific immunoglobulin G (IgG) responses, whereas fatal outcome is associated with defective humoral immunity. As B-cell epitopes on EBOV are poorly defined, we sought to identify...

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Detalles Bibliográficos
Autores principales: Becquart, Pierre, Mahlakõiv, Tanel, Nkoghe, Dieudonné, Leroy, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051576/
https://www.ncbi.nlm.nih.gov/pubmed/24914933
http://dx.doi.org/10.1371/journal.pone.0096360