Adenosine Prevents TNFα-Induced Decrease in Endothelial Mitochondrial Mass via Activation of eNOS-PGC-1α Regulatory Axis

We tested whether adenosine, a cytoprotective mediator and trigger of preconditioning, could protect endothelial cells from inflammation-induced deficits in mitochondrial biogenesis and function. We examined this question using human microvascular endothelial cells exposed to TNFα. TNFα produced tim...

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Detalles Bibliográficos
Autores principales: Kalogeris, Theodore J., Baines, Christopher, Korthuis, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051583/
https://www.ncbi.nlm.nih.gov/pubmed/24914683
http://dx.doi.org/10.1371/journal.pone.0098459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051583/
https://www.ncbi.nlm.nih.gov/pubmed/24914683
http://dx.doi.org/10.1371/journal.pone.0098459

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