Hypoxia-Inducible Factor-2α Is an Essential Catabolic Regulator of Inflammatory Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a systemic autoimmune disorder that manifests as chronic inflammation and joint tissue destruction. However, the etiology and pathogenesis of RA have not been fully elucidated. Here, we explored the role of the hypoxia-inducible factors (HIFs), HIF-1α (encoded by HIF1A)...

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Detalles Bibliográficos
Autores principales: Ryu, Je-Hwang, Chae, Chang-Suk, Kwak, Ji-Sun, Oh, Hwanhee, Shin, Youngnim, Huh, Yun Hyun, Lee, Choong-Gu, Park, Yong-Wook, Chun, Churl-Hong, Kim, Young-Myeong, Im, Sin-Hyeog, Chun, Jang-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051611/
https://www.ncbi.nlm.nih.gov/pubmed/24914685
http://dx.doi.org/10.1371/journal.pbio.1001881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051611/
https://www.ncbi.nlm.nih.gov/pubmed/24914685
http://dx.doi.org/10.1371/journal.pbio.1001881

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